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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPTOR All Species: 36.97
Human Site: T761 Identified Species: 73.94
UniProt: Q8N122 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N122 NP_065812.1 1335 149038 T761 F S P G N L S T S S S A S S T
Chimpanzee Pan troglodytes XP_001161716 1335 149161 T761 X S P G N L S T S S S A S S T
Rhesus Macaque Macaca mulatta XP_001110471 1335 148870 T761 F S P G N L S T S S S A S S T
Dog Lupus familis XP_850487 1335 149172 T761 F S P G N L S T S S S A S S T
Cat Felis silvestris
Mouse Mus musculus Q8K4Q0 1335 149453 T761 F S P G N L S T S S S A S S T
Rat Rattus norvegicus NP_001127971 1335 149475 T761 F S P G N L S T S S S A S S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426232 1335 149895 T761 F S P G N L S T S S S A S S T
Frog Xenopus laevis NP_001088177 1334 149513 T759 F S P G N L S T S S S A S S T
Zebra Danio Brachydanio rerio XP_001919288 1332 149175 T761 F S P G N L S T S S S A S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624060 1279 144157 L714 S R D R L K M L S P N N T Y N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323654 1366 149968 V786 G S D N P S V V R D G R V S T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38873 1557 177591 S917 K E L V V Y F S H I V S R Y S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.8 95.9 N.A. 96.5 96.7 N.A. N.A. 95 90.5 87.9 N.A. N.A. 55.5 N.A. N.A.
Protein Similarity: 100 99.5 99.1 98.3 N.A. 98.4 98.5 N.A. N.A. 97.6 95.9 94.6 N.A. N.A. 70.4 N.A. N.A.
P-Site Identity: 100 93.3 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: 40.8 N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: 58.2 N.A. N.A. N.A. 51 N.A.
P-Site Identity: 20 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 67 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 75 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 9 75 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 75 0 0 0 0 0 9 9 0 0 9 % N
% Pro: 0 0 75 0 9 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 0 0 0 0 9 0 0 9 9 0 0 % R
% Ser: 9 84 0 0 0 9 75 9 84 75 75 9 75 84 9 % S
% Thr: 0 0 0 0 0 0 0 75 0 0 0 0 9 0 84 % T
% Val: 0 0 0 9 9 0 9 9 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _